Api Endpoint

2s — the (most) everything API

Look up a gene by its official symbol (e.g. "TP53", "BRCA1", "CFTR") and organism (taxid, default 9606 = human), merging NCBI Gene with UniProt. Returns the gene symbol, NCBI Gene ID, full description, organism, chromosome + cytogenetic map location, alias symbols, and the curated RefSeq function summary; plus the reviewed protein from UniProt — accession, entry id, recommended protein name, length in amino acids, and the curated function description. NCBI + UniProt links. Bioinformatics, clinical-genetics research, education. Public-domain NCBI + CC-BY UniProt data. Common organism taxids: human 9606, mouse 10090, zebrafish 7955, fruit fly 7227, yeast 559292.

Open interactive test console

Offering

Provider: 2s.io
Method: GET
Offering type: Api Endpoint
Transport type: http
Category: Api
Delivery: Not provided
Pricing model: Not provided
x402 version: 2

Endpoint context

URL: https://2s.io/api/bio/gene
MIME type: application/json
First seen: 2026-10-16T02:52:34.600Z
Last seen: 2026-11-04T06:05:19.590Z
Tags: public-records, identifiers, AI-agents, us-gov-data, X402, upto-billing, ai-gateway, agent-infrastructure, AI, Crypto, Random, Search, Trading, Utility

Website

Payment pricing

x402 payment terms are the authoritative price for calling this endpoint.

Payment option 1: 0.0048 USDC
Atomic price: 4800 · Network: eip155:8453 · Asset: USDC · Scheme: exact
Payment option 2: 0.0048 USDC
Atomic price: 4800 · Network: solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp · Asset: USDC · Scheme: exact

Raw x402 terms

[
  {
    "scheme": "exact",
    "network": "eip155:8453",
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "amount": "4800",
    "payTo": "0x2b6D4988Db4723E6908Db86Ab2b8dFBc51FC32C5"
  },
  {
    "scheme": "exact",
    "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
    "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
    "amount": "4800",
    "payTo": "TW6ntaGzvj63ZgPjszd4FCGmVTGfzv1MAYZbjYcyWhn"
  }
]

Observed health

Status: Healthy
Latest latency: 87 ms
Average latency: 133 ms
HTTP status: 402
Last checked: 2026-11-04T06:05:19.585Z
Reachability: 100% over 12 checks

Latency is measured to the first response headers. A reachable result does not verify response accuracy or merchant identity.

Input schema

{
  "type": "object",
  "properties": {
    "type": {
      "const": "http"
    },
    "method": {
      "const": "GET"
    },
    "queryParams": {
      "properties": {
        "symbol": {
          "type": "string",
          "description": "Official gene symbol, e.g. \"TP53\"."
        },
        "taxid": {
          "type": "integer",
          "description": "NCBI taxonomy id (default 9606 = human).",
          "default": 9606
        }
      },
      "required": [
        "symbol"
      ]
    }
  },
  "required": [
    "type",
    "method",
    "queryParams"
  ]
}

Output schema

{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "type": "object",
  "properties": {
    "input": {
      "type": "object",
      "properties": {
        "type": {
          "const": "http"
        },
        "method": {
          "const": "GET"
        },
        "queryParams": {
          "properties": {
            "symbol": {
              "type": "string",
              "description": "Official gene symbol, e.g. \"TP53\"."
            },
            "taxid": {
              "type": "integer",
              "description": "NCBI taxonomy id (default 9606 = human).",
              "default": 9606
            }
          },
          "required": [
            "symbol"
          ]
        }
      },
      "required": [
        "type",
        "method",
        "queryParams"
      ]
    }
  },
  "required": [
    "input"
  ]
}