Api Endpoint

Saylor Innovations Bioinformatic

ClinVar variants for a gene filtered by clinical significance - counts and latest records

Open interactive test console

Offering

Provider
saylorinnovations.com
Method
GET
Offering type
Api Endpoint
Transport type
http
Category
Health And Medicine
Delivery
Not provided
Pricing model
Not provided
x402 version
2

Endpoint context

URL
https://saylorinnovations.com/api/bio/variants
MIME type
Not provided
First seen
2026-10-16T01:51:51.176Z
Last seen
Tags
bioinformatics, variants, genomics, proteins

Payment pricing

x402 payment terms are the authoritative price for calling this endpoint.

Payment option 1
0.01 USDC
Atomic price: 10000 · Network: eip155:8453 · Asset: USDC · Scheme: exact
Payment option 2
0.01 USDC
Atomic price: 10000 · Network: solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp · Asset: USDC · Scheme: exact
Raw x402 terms
[
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    "scheme": "exact",
    "network": "eip155:8453",
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "amount": "10000",
    "payTo": "0xA2A8dF0f7CaaBEa4e120a2568118f141569fc8aa"
  },
  {
    "scheme": "exact",
    "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
    "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
    "amount": "10000",
    "payTo": "7LSjfrJf8fNsB8VA9u7N3WEn25smQLpob3SvyUvXacy7"
  }
]

Observed health

Status
Healthy
Latest latency
213 ms
Average latency
1457 ms
HTTP status
402
Last checked
Reachability
100% over 5 checks

Latency is measured to the first response headers. A reachable result does not verify response accuracy or merchant identity.

Input schema

{
  "additionalProperties": false,
  "properties": {
    "method": {
      "enum": [
        "GET",
        "POST",
        "PUT",
        "PATCH",
        "DELETE",
        "HEAD"
      ],
      "type": "string"
    },
    "queryParams": {
      "properties": {
        "gene": {
          "description": "gene symbol (query)",
          "type": "string"
        },
        "significance": {
          "description": "pathogenic | likely_pathogenic | uncertain | benign | likely_benign | conflicting (query, optional)",
          "type": "string"
        }
      },
      "required": [
        "gene"
      ],
      "type": "object"
    },
    "type": {
      "const": "http",
      "type": "string"
    }
  },
  "required": [
    "type",
    "method"
  ],
  "type": "object"
}

Output schema

{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "properties": {
    "input": {
      "additionalProperties": false,
      "properties": {
        "method": {
          "enum": [
            "GET",
            "POST",
            "PUT",
            "PATCH",
            "DELETE",
            "HEAD"
          ],
          "type": "string"
        },
        "queryParams": {
          "properties": {
            "gene": {
              "description": "gene symbol (query)",
              "type": "string"
            },
            "significance": {
              "description": "pathogenic | likely_pathogenic | uncertain | benign | likely_benign | conflicting (query, optional)",
              "type": "string"
            }
          },
          "required": [
            "gene"
          ],
          "type": "object"
        },
        "type": {
          "const": "http",
          "type": "string"
        }
      },
      "required": [
        "type",
        "method"
      ],
      "type": "object"
    },
    "output": {
      "properties": {
        "example": {
          "properties": {
            "classification_counts_in_page": {
              "description": "Classification counts in page"
            },
            "count": {
              "description": "Number of items returned",
              "type": [
                "number",
                "null"
              ]
            },
            "found": {
              "description": "True when the lookup matched a record",
              "type": "boolean"
            },
            "gene": {
              "description": "Gene symbol",
              "type": [
                "string",
                "null"
              ]
            },
            "note": {
              "description": "Caveat or context for reading the result",
              "type": [
                "string",
                "null"
              ]
            },
            "significance": {
              "type": [
                "string",
                "null"
              ]
            },
            "source": {
              "description": "Data source the values come from",
              "type": [
                "string",
                "null"
              ]
            },
            "total_in_clinvar": {
              "description": "Total in clinvar",
              "type": "number"
            },
            "variants": {
              "description": "Variants",
              "items": {
                "type": "object"
              },
              "type": "array"
            }
          },
          "required": [
            "found"
          ],
          "type": "object"
        },
        "type": {
          "const": "json",
          "type": "string"
        }
      },
      "required": [
        "type"
      ],
      "type": "object"
    }
  },
  "required": [
    "input"
  ],
  "type": "object"
}