Api Endpoint

2s

Look up a protein in UniProtKB by accession (e.g. "P04637", "Q9Y6K9", "P0DTC2"). Returns the entry id, reviewed (Swiss-Prot) flag, recommended + alternative protein names, gene names, organism + taxid, sequence length and molecular weight, the curated function description, subcellular locations, Gene Ontology terms (id + term + aspect: biological_process / molecular_function / cellular_component), PDB structure ids, and keywords. Bioinformatics, structural biology, drug-target research, education. Gene-centric sibling: /api/bio/gene. CC-BY UniProt data.

Open interactive test console

Offering

Provider
2s.io
Method
GET
Offering type
Api Endpoint
Transport type
http
Category
Weather And Environment
Delivery
Not provided
Pricing model
Not provided
x402 version
2

Endpoint context

URL
https://2s.io/api/bio/protein
MIME type
application/json
First seen
2026-10-16T01:54:06.400Z
Last seen
Tags
public-records, identifiers, AI-agents, us-gov-data, X402, upto-billing, ai-gateway, agent-infrastructure

Payment pricing

x402 payment terms are the authoritative price for calling this endpoint.

Payment option 1
0.0036 USDC
Atomic price: 3600 · Network: eip155:8453 · Asset: USDC · Scheme: exact
Payment option 2
0.0036 USDC
Atomic price: 3600 · Network: solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp · Asset: USDC · Scheme: exact
Raw x402 terms
[
  {
    "scheme": "exact",
    "network": "eip155:8453",
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "amount": "3600",
    "payTo": "0x2b6D4988Db4723E6908Db86Ab2b8dFBc51FC32C5"
  },
  {
    "scheme": "exact",
    "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
    "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
    "amount": "3600",
    "payTo": "TW6ntaGzvj63ZgPjszd4FCGmVTGfzv1MAYZbjYcyWhn"
  }
]

Observed health

Status
Healthy
Latest latency
119 ms
Average latency
113 ms
HTTP status
402
Last checked
Reachability
100% over 11 checks

Latency is measured to the first response headers. A reachable result does not verify response accuracy or merchant identity.

Input schema

{
  "type": "object",
  "properties": {
    "type": {
      "const": "http"
    },
    "method": {
      "const": "GET"
    },
    "queryParams": {
      "properties": {
        "accession": {
          "type": "string",
          "description": "UniProtKB accession, e.g. \"P04637\"."
        }
      },
      "required": [
        "accession"
      ]
    }
  },
  "required": [
    "type",
    "method",
    "queryParams"
  ]
}

Output schema

{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "type": "object",
  "properties": {
    "input": {
      "type": "object",
      "properties": {
        "type": {
          "const": "http"
        },
        "method": {
          "const": "GET"
        },
        "queryParams": {
          "properties": {
            "accession": {
              "type": "string",
              "description": "UniProtKB accession, e.g. \"P04637\"."
            }
          },
          "required": [
            "accession"
          ]
        }
      },
      "required": [
        "type",
        "method",
        "queryParams"
      ]
    }
  },
  "required": [
    "input"
  ]
}