bio.halowerk.com
Compares one guide with caller-supplied candidate protospacers, weights mismatches in the guide’s final ten positions twice, applies a simple NGG PAM penalty, and ranks a transparent similarity score. It does not search a genome, model bulges, chromatin or nuclease-specific biology, and must not be used as a clinical or laboratory safety decision.
Offering
- Provider
- bio.halowerk.com
- Method
- POST
- Offering type
- Api Endpoint
- Transport type
- http
- Category
- Science And Education
- Delivery
- Not provided
- Pricing model
- Not provided
- x402 version
- 2
Endpoint context
- URL
https://bio.halowerk.com/v1/crispr-offtarget- MIME type
- Not provided
- First seen
- 2026-10-16T01:54:06.400Z
- Last seen
- Tags
- None supplied
Payment pricing
x402 payment terms are the authoritative price for calling this endpoint.
- Payment option 1
- 0.004 USDC
Atomic price: 4000 · Network: eip155:8453 · Asset: USDC · Scheme: exact
Raw x402 terms
[
{
"scheme": "exact",
"network": "eip155:8453",
"asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
"amount": "4000",
"payTo": "0x2880EdfFF13100677Bf97A3CBdF3Bc34771C4E5E"
}
]Observed health
- Status
- Healthy
- Latest latency
- 318 ms
- Average latency
- 660 ms
- HTTP status
- 204
- Last checked
- Reachability
- 100% over 9 checks
Latency is measured to the first response headers. A reachable result does not verify response accuracy or merchant identity.
Input schema
{
"additionalProperties": false,
"properties": {
"body": {
"additionalProperties": false,
"properties": {
"candidates": {
"items": {
"additionalProperties": false,
"properties": {
"id": {
"maxLength": 128,
"minLength": 1,
"type": "string"
},
"pam": {
"maxLength": 8,
"minLength": 2,
"pattern": "^[ACGT]+$",
"type": "string"
},
"protospacer": {
"maxLength": 30,
"minLength": 17,
"pattern": "^[ACGT]+$",
"type": "string"
}
},
"required": [
"id",
"protospacer",
"pam"
],
"type": "object"
},
"maxItems": 1000,
"minItems": 1,
"type": "array"
},
"guide": {
"description": "Guide sequence written 5-prime to 3-prime.",
"maxLength": 30,
"minLength": 17,
"pattern": "^[ACGT]+$",
"type": "string"
}
},
"required": [
"guide",
"candidates"
],
"type": "object"
},
"bodyType": {
"enum": [
"json",
"form-data",
"text"
],
"type": "string"
},
"method": {
"enum": [
"POST",
"PUT",
"PATCH"
],
"type": "string"
},
"type": {
"const": "http",
"type": "string"
}
},
"required": [
"type",
"method",
"bodyType",
"body"
],
"type": "object"
}Output schema
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"properties": {
"input": {
"additionalProperties": false,
"properties": {
"body": {
"additionalProperties": false,
"properties": {
"candidates": {
"items": {
"additionalProperties": false,
"properties": {
"id": {
"maxLength": 128,
"minLength": 1,
"type": "string"
},
"pam": {
"maxLength": 8,
"minLength": 2,
"pattern": "^[ACGT]+$",
"type": "string"
},
"protospacer": {
"maxLength": 30,
"minLength": 17,
"pattern": "^[ACGT]+$",
"type": "string"
}
},
"required": [
"id",
"protospacer",
"pam"
],
"type": "object"
},
"maxItems": 1000,
"minItems": 1,
"type": "array"
},
"guide": {
"description": "Guide sequence written 5-prime to 3-prime.",
"maxLength": 30,
"minLength": 17,
"pattern": "^[ACGT]+$",
"type": "string"
}
},
"required": [
"guide",
"candidates"
],
"type": "object"
},
"bodyType": {
"enum": [
"json",
"form-data",
"text"
],
"type": "string"
},
"method": {
"enum": [
"POST",
"PUT",
"PATCH"
],
"type": "string"
},
"type": {
"const": "http",
"type": "string"
}
},
"required": [
"type",
"method",
"bodyType",
"body"
],
"type": "object"
}
},
"required": [
"input"
],
"type": "object"
}